[Bioinformatics](/majors/biological-biomedical-sciences/biomathematics-bioinformatics-computational-biology/bioinformatics/) is a field worth comparing on the balance of cost and outcomes. The schools below stand out for delivering a strong bioinformatics education at a price that pays off.
For its 2027 best-value ranking, College Factual looked at 7 schools to find the best return on investment for bioinformatics students.
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If you want to know which schools deliver the best value for the bioinformatics degrees they offer, see the list below.
University Of Illinois At Chicago tops our 2027 list of the best value bioinformatics schools in the Great Lakes Region. Located in the city of Chicago, University Of Illinois At Chicago is a very large public university. Students from in state pay about $15,949 in tuition and fees, compared with $32,009 for out-of-state students. Bioinformatics graduates carry a median of $20,115 in student loans. Bioinformatics graduates of University Of Illinois At Chicago earn a median of $61,829 early in their careers. Set against $20,115 in median debt, that is a healthy payoff. Roughly 77% of applicants are accepted.
Students looking for strong value in bioinformatics will find it at University Of Michigan Ann Arbor, which ranked #2. University Of Michigan Ann Arbor is a very large public school located in the city of Ann Arbor. The average in-state cost of tuition and fees is $18,848, while out-of-state students pay about $63,081. Bioinformatics graduates carry a median of $19,137 in student loans. Bioinformatics graduates of University Of Michigan Ann Arbor earn a median of $71,336 early in their careers. Weighed against typical debt, the earnings make a compelling case for value. The acceptance rate is 16%.
Students looking for strong value in bioinformatics will find it at Indiana University Purdue University Indianapolis, which ranked #3. Indiana University Purdue University Indianapolis is a very large public school located in the city of Indianapolis. Students from in state pay about $10,762 in tuition and fees, compared with $34,891 for out-of-state students. Typical student debt for bioinformatics graduates is $23,146. Early-career bioinformatics graduates make about $56,930. Set against $23,146 in median debt, that is a healthy payoff. The acceptance rate is 76%.
University Of Chicago is a great value for students pursuing a degree in bioinformatics, landing the #4 spot this year. University Of Chicago is a very large private not-for-profit school located in the city of Chicago. The average in-state cost of tuition and fees is $69,324. Bioinformatics graduates carry a median of $15,854 in student loans. Bioinformatics graduates of University Of Chicago earn a median of $99,193 early in their careers. Set against $15,854 in median debt, that is a healthy payoff. Roughly 4% of applicants are accepted.
Grand Valley State University came in at #5 on our 2027 list of the best value bioinformatics schools. Grand Valley State University is a very large public school located in the town of Allendale. Students from in state pay about $15,502 in tuition and fees, with out-of-state students paying around $21,894. Students borrow a median of $26,378 to complete the bioinformatics program here. Soon after graduation, bioinformatics degree recipients from Grand Valley State University generally make around $74,986. Set against $26,378 in median debt, that is a healthy payoff. The acceptance rate is 83%.
Loyola University Chicago landed the #6 spot for bioinformatics value this year. Located in the city of Chicago, Loyola University Chicago is a large private not-for-profit university. Expect in-state tuition and fees of around $53,710. Typical student debt for bioinformatics graduates is $23,521. Early-career bioinformatics graduates make about $58,568. Weighed against typical debt, the earnings make a compelling case for value. Loyola University Chicago admits about 82% of applicants.
Case Western Reserve University landed the #7 spot for bioinformatics value this year. Case Western Reserve University is a large private not-for-profit school located in the city of Cleveland. The average in-state cost of tuition and fees is $66,608. Bioinformatics graduates carry a median of $25,106 in student loans. Bioinformatics graduates of Case Western Reserve University earn a median of $74,459 early in their careers. Set against $25,106 in median debt, that is a healthy payoff. Roughly 36% of applicants are accepted.
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Notes and References
This ranking is produced by College Factual (MF_RANKING_2025), 2027 edition. Schools are scored on the balance of cost (tuition and student debt) against student outcomes (post-graduation earnings) — a measure of return on investment, drawn primarily from the U.S. Department of Education (IPEDS and College Scorecard).
Ranking method: College Major Best Value · 7 schools evaluated.
*Averages shown above reflect the top 7 ranked schools only.
- The Integrated Postsecondary Education Data System (IPEDS) from the National Center for Education Statistics (NCES), a branch of the U.S. Department of Education (DOE), serves as the core of our data about colleges.
- Some other college data, including much of the graduate earnings data, comes from the U.S. Department of Education’s (College Scorecard).
More about our data sources and methodologies.
