[Biomathematics & Bioinformatics](/majors/biological-biomedical-sciences/biomathematics-bioinformatics-computational-biology/) degree programs vary widely in price and payoff across the country. A high-value program keeps cost low while graduates go on to earn well.
College Factual analyzed 6 schools to build this 2027 ranking of the best value biomathematics & bioinformatics schools.
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Below are the schools that deliver the strongest value in biomathematics & bioinformatics, balancing cost against outcomes.
Juniata College earned the #1 spot for value among biomathematics & bioinformatics schools in Pennsylvania. Set in the town of Huntingdon, Juniata College is a small private not-for-profit institution. Students from in state pay about $58,580 in tuition and fees. Students borrow a median of $26,976 to complete the biomathematics & bioinformatics program here. Biomathematics & Bioinformatics graduates of Juniata College earn a median of $30,552 early in their careers. That is a strong return on a $26,976 median debt. Juniata College admits about 79% of applicants.
A rank of #2 makes Temple University one of the best values for biomathematics & bioinformatics. Temple University is a very large public school located in the city of Philadelphia. Expect in-state tuition and fees of around $23,005, while out-of-state students pay about $38,805. Biomathematics & Bioinformatics graduates carry a median of $26,259 in student loans. Early-career biomathematics & bioinformatics graduates make about $54,642. That is a strong return on a $26,259 median debt. Temple University admits about 80% of applicants.
University Of Pennsylvania came in at #3 on our 2027 list of the best value biomathematics & bioinformatics schools. University Of Pennsylvania is a very large private not-for-profit school located in the city of Philadelphia. Expect in-state tuition and fees of around $68,686. Typical student debt for biomathematics & bioinformatics graduates is $16,155. Biomathematics & Bioinformatics graduates of University Of Pennsylvania earn a median of $99,682 early in their careers. Set against $16,155 in median debt, that is a healthy payoff. University Of Pennsylvania admits about 5% of applicants.
A rank of #4 makes University Of Pittsburgh Pittsburgh Campus one of the best values for biomathematics & bioinformatics. Set in the city of Pittsburgh, University Of Pittsburgh Pittsburgh Campus is a very large public institution. The average in-state cost of tuition and fees is $21,926, while out-of-state students pay about $41,430. Typical student debt for biomathematics & bioinformatics graduates is $24,958. Early-career biomathematics & bioinformatics graduates make about $56,926. That is a strong return on a $24,958 median debt. Roughly 58% of applicants are accepted.
A rank of #5 makes Carnegie Mellon University one of the best values for biomathematics & bioinformatics. Located in the city of Pittsburgh, Carnegie Mellon University is a large private not-for-profit university. In-state tuition and fees average $65,636. Typical student debt for biomathematics & bioinformatics graduates is $23,529. Biomathematics & Bioinformatics graduates of Carnegie Mellon University earn a median of $89,327 early in their careers. That is a strong return on a $23,529 median debt. The acceptance rate is 12%.
Pennsylvania State University Main Campus came in at #6 for value in biomathematics & bioinformatics this year. Pennsylvania State University Main Campus is a very large public school located in the city of University Park. In-state tuition and fees average $20,644, with out-of-state students paying around $41,790. Biomathematics & Bioinformatics graduates carry a median of $25,266 in student loans. Early-career biomathematics & bioinformatics graduates make about $60,523. Weighed against typical debt, the earnings make a compelling case for value. Pennsylvania State University Main Campus admits about 61% of applicants.
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Notes and References
The ranking above is published by College Factual (MF_RANKING_2025), 2027 edition. The methodology weighs the cost of a degree against the earnings graduates go on to achieve, drawn primarily from the U.S. Department of Education (IPEDS and College Scorecard).
Ranking method: College Major Best Value · 6 schools evaluated.
*Averages shown above reflect the top 6 ranked schools only.
- The Integrated Postsecondary Education Data System (IPEDS) from the National Center for Education Statistics (NCES), a branch of the U.S. Department of Education (DOE), serves as the core of our data about colleges.
- Some other college data, including much of the graduate earnings data, comes from the U.S. Department of Education’s (College Scorecard).
More about our data sources and methodologies.
