
[Medical Informatics](/majors/health-care-professions/medical-illustration-informatics/medical-informatics/) degree programs vary widely in price and payoff across the country. The best values balance affordable tuition against strong post-graduation earnings.
College Factual analyzed 6 schools to build this 2027 ranking of the best value medical informatics schools.
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If you want to know which schools deliver the best value for the medical informatics degrees they offer, see the list below.
University Of South Carolina Upstate earned the #1 spot for value among medical informatics schools in the United States. Located in the suburb of Spartanburg, University Of South Carolina Upstate is a moderately-sized public university. Students from in state pay about $11,588 in tuition and fees, with out-of-state students paying around $23,090. Medical Informatics graduates carry a median of $30,289 in student loans. Early-career medical informatics graduates make about $39,473. Weighed against typical debt, the earnings make a compelling case for value. University Of South Carolina Upstate admits about 67% of applicants.
George Mason University came in at #2 on our 2027 list of the best value medical informatics schools. George Mason University is a very large public school located in the suburb of Fairfax. Expect in-state tuition and fees of around $14,220, with out-of-state students paying around $38,688. Typical student debt for medical informatics graduates is $23,529. Soon after graduation, medical informatics degree recipients from George Mason University generally make around $76,595. Weighed against typical debt, the earnings make a compelling case for value. Roughly 88% of applicants are accepted.
Indiana University Of Pennsylvania Main Campus is a great value for students pursuing a degree in medical informatics, landing the #3 spot this year. Located in the town of Indiana, Indiana University Of Pennsylvania Main Campus is a large public university. Expect in-state tuition and fees of around $11,380, compared with $16,297 for out-of-state students. Medical Informatics graduates carry a median of $26,513 in student loans. Medical Informatics graduates of Indiana University Of Pennsylvania Main Campus earn a median of $42,972 early in their careers. That is a strong return on a $26,513 median debt. Roughly 91% of applicants are accepted.
University Of South Alabama is a great value for students pursuing a degree in medical informatics, landing the #4 spot this year. Set in the city of Mobile, University Of South Alabama is a large public institution. Expect in-state tuition and fees of around $10,116, compared with $19,092 for out-of-state students. Typical student debt for medical informatics graduates is $26,513. Medical Informatics graduates of University Of South Alabama earn a median of $51,592 early in their careers. Weighed against typical debt, the earnings make a compelling case for value. Roughly 71% of applicants are accepted.
Students looking for strong value in medical informatics will find it at Temple University, which ranked #5. Located in the city of Philadelphia, Temple University is a very large public university. The average in-state cost of tuition and fees is $23,005, while out-of-state students pay about $38,805. Medical Informatics graduates carry a median of $25,000 in student loans. Medical Informatics graduates of Temple University earn a median of $52,611 early in their careers. Weighed against typical debt, the earnings make a compelling case for value. Temple University admits about 80% of applicants.
Rochester Institute Of Technology came in at #6 for value in medical informatics this year. Set in the suburb of Rochester, Rochester Institute Of Technology is a large private not-for-profit institution. Expect in-state tuition and fees of around $59,210. Typical student debt for medical informatics graduates is $27,491. Medical Informatics graduates of Rochester Institute Of Technology earn a median of $25,345 early in their careers. That is a strong return on a $27,491 median debt. Roughly 67% of applicants are accepted.
Explore the best-value medical informatics schools at other degree levels:
View All Medical Informatics Rankings >
Notes and References
The ranking above is published by College Factual (MF_RANKING_2025), 2027 edition. Schools are scored on the balance of cost (tuition and student debt) against student outcomes (post-graduation earnings) — a measure of return on investment, drawn primarily from the U.S. Department of Education (IPEDS and College Scorecard).
Ranking method: College Major Best Value · 6 schools evaluated.
*Averages shown above reflect the top 6 ranked schools only.
- The Integrated Postsecondary Education Data System (IPEDS) from the National Center for Education Statistics (NCES), a branch of the U.S. Department of Education (DOE), serves as the core of our data about colleges.
- Some other college data, including much of the graduate earnings data, comes from the U.S. Department of Education’s (College Scorecard).
More about our data sources and methodologies.