2027 Best Value Medicine Schools in the The Plains States Region

[Medicine](/majors/health-care-professions/medicine/) programs reward a close look at where your money goes furthest. The schools below stand out for delivering a strong medicine education at a price that pays off.
College Factual analyzed 10 schools to build this 2027 ranking of the best value medicine schools.
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2027 Best Value Medicine Schools in the The Plains States Region
If you want to know which schools deliver the best value for the medicine degrees they offer, see the list below.
Best Value Medicine Schools
Leading the list is University Of Minnesota Twin Cities, our #1 best value for medicine in the The Plains States Region. Located in the city of Minneapolis, University Of Minnesota Twin Cities is a very large public university. Students from in state pay about $17,214 in tuition and fees, with out-of-state students paying around $38,362. Students borrow a median of $21,577 to complete the medicine program here. Soon after graduation, medicine degree recipients from University Of Minnesota Twin Cities generally make around $65,924. Set against $21,577 in median debt, that is a healthy payoff. The acceptance rate is 80%.
University Of Missouri Kansas City is a great value for students pursuing a degree in medicine, landing the #2 spot this year. Set in the city of Kansas City, University Of Missouri Kansas City is a large public institution. The average in-state cost of tuition and fees is $13,371, while out-of-state students pay about $32,271. Typical student debt for medicine graduates is $23,741. Early-career medicine graduates make about $63,219. Set against $23,741 in median debt, that is a healthy payoff. University Of Missouri Kansas City admits about 72% of applicants.
The strong cost-to-outcome balance at University Of Kansas earned it the #3 place for medicine. Set in the city of Lawrence, University Of Kansas is a very large public institution. Students from in state pay about $12,102 in tuition and fees, while out-of-state students pay about $30,432. Medicine graduates carry a median of $23,608 in student loans. Early-career medicine graduates make about $63,138. Weighed against typical debt, the earnings make a compelling case for value. University Of Kansas admits about 94% of applicants.
A rank of #4 makes University Of North Dakota one of the best values for medicine. Set in the city of Grand Forks, University Of North Dakota is a large public institution. The average in-state cost of tuition and fees is $10,951, compared with $15,570 for out-of-state students. Typical student debt for medicine graduates is $25,110. Soon after graduation, medicine degree recipients from University Of North Dakota generally make around $66,463. Set against $25,110 in median debt, that is a healthy payoff. The acceptance rate is 77%.
A rank of #5 makes University Of South Dakota one of the best values for medicine. Located in the town of Vermillion, University Of South Dakota is a large public university. Students from in state pay about $9,432 in tuition and fees, compared with $12,942 for out-of-state students. Medicine graduates carry a median of $26,322 in student loans. Early-career medicine graduates make about $51,566. That is a strong return on a $26,322 median debt. The acceptance rate is 99%.
University Of Missouri Columbia came in at #6 for value in medicine this year. Set in the city of Columbia, University Of Missouri Columbia is a very large public institution. In-state tuition and fees average $14,837, with out-of-state students paying around $36,056. Students borrow a median of $21,818 to complete the medicine program here. Early-career medicine graduates make about $63,656. Set against $21,818 in median debt, that is a healthy payoff. Roughly 78% of applicants are accepted.
Washington University In St Louis landed the #7 spot for medicine value this year. Washington University In St Louis is a large private not-for-profit school located in the suburb of St. Louis. In-state tuition and fees average $65,790. Students borrow a median of $17,553 to complete the medicine program here. Early-career medicine graduates make about $66,880. Set against $17,553 in median debt, that is a healthy payoff. The acceptance rate is 12%.
University Of Iowa came in at #8 for value in medicine this year. Located in the city of Iowa City, University Of Iowa is a very large public university. Expect in-state tuition and fees of around $11,283, compared with $33,371 for out-of-state students. Medicine graduates carry a median of $24,463 in student loans. Soon after graduation, medicine degree recipients from University Of Iowa generally make around $65,889. Weighed against typical debt, the earnings make a compelling case for value. Roughly 84% of applicants are accepted.
Saint Louis University Main Campus ranked #9 on our 2027 list of the best value medicine schools. Saint Louis University Main Campus is a large private not-for-profit school located in the city of Saint Louis. The average in-state cost of tuition and fees is $55,760. Medicine graduates carry a median of $26,586 in student loans. Medicine graduates of Saint Louis University Main Campus earn a median of $65,402 early in their careers. Set against $26,586 in median debt, that is a healthy payoff. The acceptance rate is 75%.
Creighton University earned the #10 position for value in medicine this year. Creighton University is a large private not-for-profit school located in the city of Omaha. In-state tuition and fees average $48,856. Students borrow a median of $25,831 to complete the medicine program here. Soon after graduation, medicine degree recipients from Creighton University generally make around $66,245. That is a strong return on a $25,831 median debt. Creighton University admits about 80% of applicants.
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Notes and References
This list is compiled by College Factual (MF_RANKING_2025), 2027 edition. Schools are scored on the balance of cost (tuition and student debt) against student outcomes (post-graduation earnings) — a measure of return on investment, drawn primarily from the U.S. Department of Education (IPEDS and College Scorecard).
Ranking method: College Major Best Value · 10 schools evaluated.
*Averages shown above reflect the top 10 ranked schools only.
- The Integrated Postsecondary Education Data System (IPEDS) from the National Center for Education Statistics (NCES), a branch of the U.S. Department of Education (DOE), serves as the core of our data about colleges.
- Some other college data, including much of the graduate earnings data, comes from the U.S. Department of Education’s (College Scorecard).
More about our data sources and methodologies.