[Biomathematics & Bioinformatics](/majors/biological-biomedical-sciences/biomathematics-bioinformatics-computational-biology/) programs reward a close look at where your money goes furthest. The schools below stand out for delivering a strong biomathematics & bioinformatics education at a price that pays off.
For its 2026 best-value ranking, College Factual looked at 25 schools to find the best return on investment for biomathematics & bioinformatics students.
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Below are the schools that deliver the strongest value in biomathematics & bioinformatics, balancing cost against outcomes.
University Of California San Diego tops our 2026 list of the best value biomathematics & bioinformatics schools in the Far Western Region. Located in the city of La Jolla, University Of California San Diego is a very large public university. In-state tuition and fees average $15,788, with out-of-state students paying around $47,676. Biomathematics & Bioinformatics graduates carry a median of $19,724 in student loans. Early-career biomathematics & bioinformatics graduates make about $76,592. Set against $19,724 in median debt, that is a healthy payoff. The acceptance rate is 27%.
University Of California Irvine came in at #2 on our 2026 list of the best value biomathematics & bioinformatics schools. Set in the city of Irvine, University Of California Irvine is a very large public institution. Students from in state pay about $14,752 in tuition and fees, with out-of-state students paying around $46,640. Typical student debt for biomathematics & bioinformatics graduates is $16,539. Biomathematics & Bioinformatics graduates of University Of California Irvine earn a median of $50,958 early in their careers. That is a strong return on a $16,539 median debt. University Of California Irvine admits about 29% of applicants.
A rank of #3 makes University Of Washington Seattle Campus one of the best values for biomathematics & bioinformatics. Set in the city of Seattle, University Of Washington Seattle Campus is a very large public institution. In-state tuition and fees average $12,973, with out-of-state students paying around $43,209. Biomathematics & Bioinformatics graduates carry a median of $16,481 in student loans. Biomathematics & Bioinformatics graduates of University Of Washington Seattle Campus earn a median of $65,681 early in their careers. That is a strong return on a $16,481 median debt. The acceptance rate is 39%.
Portland State University came in at #4 on our 2026 list of the best value biomathematics & bioinformatics schools. Set in the city of Portland, Portland State University is a very large public institution. In-state tuition and fees average $11,118, with out-of-state students paying around $29,136. Biomathematics & Bioinformatics graduates carry a median of $26,475 in student loans. Soon after graduation, biomathematics & bioinformatics degree recipients from Portland State University generally make around $47,717. Set against $26,475 in median debt, that is a healthy payoff. Roughly 91% of applicants are accepted.
University Of California Los Angeles came in at #5 on our 2026 list of the best value biomathematics & bioinformatics schools. University Of California Los Angeles is a very large public school located in the city of Los Angeles. In-state tuition and fees average $14,233, with out-of-state students paying around $46,121. Students borrow a median of $16,097 to complete the biomathematics & bioinformatics program here. Soon after graduation, biomathematics & bioinformatics degree recipients from University Of California Los Angeles generally make around $63,833. That is a strong return on a $16,097 median debt. The acceptance rate is 9%.
University Of California Berkeley landed the #6 spot for biomathematics & bioinformatics value this year. Set in the city of Berkeley, University Of California Berkeley is a very large public institution. In-state tuition and fees average $15,377, compared with $47,265 for out-of-state students. Students borrow a median of $14,238 to complete the biomathematics & bioinformatics program here. Soon after graduation, biomathematics & bioinformatics degree recipients from University Of California Berkeley generally make around $70,847. Set against $14,238 in median debt, that is a healthy payoff. Roughly 11% of applicants are accepted.
San Diego State University placed #7 among the best values for biomathematics & bioinformatics. Set in the city of San Diego, San Diego State University is a very large public institution. Expect in-state tuition and fees of around $8,728, compared with $21,328 for out-of-state students. Biomathematics & Bioinformatics graduates carry a median of $16,417 in student loans. Early-career biomathematics & bioinformatics graduates make about $51,162. Weighed against typical debt, the earnings make a compelling case for value. Roughly 36% of applicants are accepted.
University Of California Santa Cruz came in at #8 for value in biomathematics & bioinformatics this year. Located in the city of Santa Cruz, University Of California Santa Cruz is a very large public university. In-state tuition and fees average $15,035, while out-of-state students pay about $46,923. Biomathematics & Bioinformatics graduates carry a median of $18,559 in student loans. Soon after graduation, biomathematics & bioinformatics degree recipients from University Of California Santa Cruz generally make around $40,920. Weighed against typical debt, the earnings make a compelling case for value. University Of California Santa Cruz admits about 66% of applicants.
University Of Southern California placed #9 among the best values for biomathematics & bioinformatics. Set in the city of Los Angeles, University Of Southern California is a very large private not-for-profit institution. Students from in state pay about $71,647 in tuition and fees. Students borrow a median of $15,625 to complete the biomathematics & bioinformatics program here. Soon after graduation, biomathematics & bioinformatics degree recipients from University Of Southern California generally make around $58,044. Set against $15,625 in median debt, that is a healthy payoff. The acceptance rate is 10%.
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Notes and References
This ranking is produced by College Factual (MF_RANKING_2025), 2026 edition. The methodology weighs the cost of a degree against the earnings graduates go on to achieve, drawn primarily from the U.S. Department of Education (IPEDS and College Scorecard).
Ranking method: College Major Best Value · 25 schools evaluated.
*Averages shown above reflect the top 7 ranked schools only.
- The Integrated Postsecondary Education Data System (IPEDS) from the National Center for Education Statistics (NCES), a branch of the U.S. Department of Education (DOE), serves as the core of our data about colleges.
- Some other college data, including much of the graduate earnings data, comes from the U.S. Department of Education’s (College Scorecard).
More about our data sources and methodologies.
