[Biomathematics & Bioinformatics](/majors/biological-biomedical-sciences/biomathematics-bioinformatics-computational-biology/) programs reward a close look at where your money goes furthest. The schools below stand out for delivering a strong biomathematics & bioinformatics education at a price that pays off.
For its 2026 best-value ranking, College Factual looked at 17 schools to find the best return on investment for biomathematics & bioinformatics students.
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If you want to know which schools deliver the best value for the biomathematics & bioinformatics degrees they offer, see the list below.
University Of California San Diego tops our 2026 list of the best value biomathematics & bioinformatics schools in California. Set in the city of La Jolla, University Of California San Diego is a very large public institution. Students from in state pay about $15,788 in tuition and fees, with out-of-state students paying around $47,676. Students borrow a median of $19,724 to complete the biomathematics & bioinformatics program here. Early-career biomathematics & bioinformatics graduates make about $76,592. That is a strong return on a $19,724 median debt. University Of California San Diego admits about 27% of applicants.
Students looking for strong value in biomathematics & bioinformatics will find it at University Of California Irvine, which ranked #2. University Of California Irvine is a very large public school located in the city of Irvine. Students from in state pay about $14,752 in tuition and fees, compared with $46,640 for out-of-state students. Typical student debt for biomathematics & bioinformatics graduates is $16,539. Early-career biomathematics & bioinformatics graduates make about $50,958. Weighed against typical debt, the earnings make a compelling case for value. University Of California Irvine admits about 29% of applicants.
The strong cost-to-outcome balance at University Of California Los Angeles earned it the #3 place for biomathematics & bioinformatics. University Of California Los Angeles is a very large public school located in the city of Los Angeles. Students from in state pay about $14,233 in tuition and fees, compared with $46,121 for out-of-state students. Typical student debt for biomathematics & bioinformatics graduates is $16,097. Early-career biomathematics & bioinformatics graduates make about $63,833. Set against $16,097 in median debt, that is a healthy payoff. Roughly 9% of applicants are accepted.
University Of California Berkeley came in at #4 on our 2026 list of the best value biomathematics & bioinformatics schools. University Of California Berkeley is a very large public school located in the city of Berkeley. Students from in state pay about $15,377 in tuition and fees, compared with $47,265 for out-of-state students. Students borrow a median of $14,238 to complete the biomathematics & bioinformatics program here. Biomathematics & Bioinformatics graduates of University Of California Berkeley earn a median of $70,847 early in their careers. Weighed against typical debt, the earnings make a compelling case for value. Roughly 11% of applicants are accepted.
The strong cost-to-outcome balance at San Diego State University earned it the #5 place for biomathematics & bioinformatics. Located in the city of San Diego, San Diego State University is a very large public university. Students from in state pay about $8,728 in tuition and fees, while out-of-state students pay about $21,328. Biomathematics & Bioinformatics graduates carry a median of $16,417 in student loans. Soon after graduation, biomathematics & bioinformatics degree recipients from San Diego State University generally make around $51,162. Weighed against typical debt, the earnings make a compelling case for value. The acceptance rate is 36%.
University Of California Santa Cruz earned the #6 position for value in biomathematics & bioinformatics this year. Located in the city of Santa Cruz, University Of California Santa Cruz is a very large public university. In-state tuition and fees average $15,035, compared with $46,923 for out-of-state students. Biomathematics & Bioinformatics graduates carry a median of $18,559 in student loans. Soon after graduation, biomathematics & bioinformatics degree recipients from University Of California Santa Cruz generally make around $40,920. Set against $18,559 in median debt, that is a healthy payoff. The acceptance rate is 66%.
University Of Southern California came in at #7 for value in biomathematics & bioinformatics this year. Set in the city of Los Angeles, University Of Southern California is a very large private not-for-profit institution. Expect in-state tuition and fees of around $71,647. Students borrow a median of $15,625 to complete the biomathematics & bioinformatics program here. Early-career biomathematics & bioinformatics graduates make about $58,044. Set against $15,625 in median debt, that is a healthy payoff. Roughly 10% of applicants are accepted.
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Notes and References
This list is compiled by College Factual (MF_RANKING_2025), 2026 edition. The methodology weighs the cost of a degree against the earnings graduates go on to achieve, drawn primarily from the U.S. Department of Education (IPEDS and College Scorecard).
Ranking method: College Major Best Value · 17 schools evaluated.
*Averages shown above reflect the top 6 ranked schools only.
- The Integrated Postsecondary Education Data System (IPEDS) from the National Center for Education Statistics (NCES), a branch of the U.S. Department of Education (DOE), serves as the core of our data about colleges.
- Some other college data, including much of the graduate earnings data, comes from the U.S. Department of Education’s (College Scorecard).
More about our data sources and methodologies.
