[Biomathematics & Bioinformatics](/majors/biological-biomedical-sciences/biomathematics-bioinformatics-computational-biology/) degree programs vary widely in price and payoff across the country. A high-value program keeps cost low while graduates go on to earn well.
College Factual analyzed 7 schools to build this 2026 ranking of the best value biomathematics & bioinformatics schools.
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If you want to know which schools deliver the best value for the biomathematics & bioinformatics degrees they offer, see the list below.
University Of Illinois At Chicago earned the #1 spot for value among biomathematics & bioinformatics schools in Illinois. Located in the city of Chicago, University Of Illinois At Chicago is a very large public university. The average in-state cost of tuition and fees is $15,949, while out-of-state students pay about $32,009. Typical student debt for biomathematics & bioinformatics graduates is $20,115. Soon after graduation, biomathematics & bioinformatics degree recipients from University Of Illinois At Chicago generally make around $61,829. Set against $20,115 in median debt, that is a healthy payoff. Roughly 77% of applicants are accepted.
The strong cost-to-outcome balance at University Of Chicago earned it the #2 place for biomathematics & bioinformatics. Set in the city of Chicago, University Of Chicago is a very large private not-for-profit institution. The average in-state cost of tuition and fees is $69,324. Students borrow a median of $15,854 to complete the biomathematics & bioinformatics program here. Soon after graduation, biomathematics & bioinformatics degree recipients from University Of Chicago generally make around $99,193. That is a strong return on a $15,854 median debt. Roughly 4% of applicants are accepted.
Students looking for strong value in biomathematics & bioinformatics will find it at Loyola University Chicago, which ranked #3. Set in the city of Chicago, Loyola University Chicago is a large private not-for-profit institution. Students from in state pay about $53,710 in tuition and fees. Biomathematics & Bioinformatics graduates carry a median of $23,521 in student loans. Soon after graduation, biomathematics & bioinformatics degree recipients from Loyola University Chicago generally make around $58,568. Weighed against typical debt, the earnings make a compelling case for value. Roughly 82% of applicants are accepted.
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Notes and References
This list is compiled by College Factual (MF_RANKING_2025), 2026 edition. Schools are scored on the balance of cost (tuition and student debt) against student outcomes (post-graduation earnings) — a measure of return on investment, drawn primarily from the U.S. Department of Education (IPEDS and College Scorecard).
Ranking method: College Major Best Value · 7 schools evaluated.
*Averages shown above reflect the top 3 ranked schools only.
- The Integrated Postsecondary Education Data System (IPEDS) from the National Center for Education Statistics (NCES), a branch of the U.S. Department of Education (DOE), serves as the core of our data about colleges.
- Some other college data, including much of the graduate earnings data, comes from the U.S. Department of Education’s (College Scorecard).
More about our data sources and methodologies.
