2026 Highest Paid Medicine Grads in the The Plains States Region

[Medicine](/majors/health-care-professions/medicine/) programs reward a close look at where graduates go on to earn the most. A top-earning program sends graduates into careers with strong starting pay.
For its 2026 highest-paid-graduates ranking, College Factual looked at 15 schools to find where medicine graduates earn the most.
What’s on this page:
2026 Highest Paid Medicine Grads in the The Plains States Region
Below are the schools whose medicine graduates go on to earn the most.
Highest Paid Medicine Graduates
University Of South Dakota earned the #1 spot for highest-paid medicine graduates in the The Plains States Region. University Of South Dakota is a public school located in the town of Vermillion. Early-career medicine graduates from University Of South Dakota make a median of around $221,069 per year.
Des Moines University Osteopathic Medical Center came in at #2 on our 2026 list of the highest-paying medicine schools. Located in the rural area of West Des Moines, Des Moines University Osteopathic Medical Center is a private not-for-profit institution. After graduating, medicine degree recipients from Des Moines University Osteopathic Medical Center typically earn about $230,347 annually.
Strong graduate earnings at A T Still University Of Health Sciences earned it the #3 place for medicine. Set in the town of Kirksville, A T Still University Of Health Sciences is a private not-for-profit institution. Students who complete the medicine program here go on to a median salary of roughly $228,706.
Students chasing top earnings in medicine will find them at University Of Minnesota Twin Cities, which ranked #4. University Of Minnesota Twin Cities is a public school located in the city of Minneapolis. After graduating, medicine degree recipients from University Of Minnesota Twin Cities typically earn about $205,382 annually.
Strong graduate earnings at University Of Nebraska Medical Center earned it the #5 place for medicine. Set in the city of Omaha, University Of Nebraska Medical Center is a public institution. Students who complete the medicine program here go on to a median salary of roughly $203,229.
Kansas City University Of Medicine And Biosciences ranked #6 on our 2026 list of the highest-paying medicine schools. Located in the city of Kansas City, Kansas City University Of Medicine And Biosciences is a private not-for-profit institution. Medicine graduates of Kansas City University Of Medicine And Biosciences earn a median of about $190,556 a year early in their careers.
Creighton University placed #7 among the highest-paying schools for medicine. Creighton University is a private not-for-profit school located in the city of Omaha. After graduating, medicine degree recipients from Creighton University typically earn about $180,260 annually.
University Of Kansas landed the #8 spot for medicine salaries this year. Set in the city of Lawrence, University Of Kansas is a public institution. Medicine graduates of University Of Kansas earn a median of about $183,730 a year early in their careers.
University Of Iowa landed the #9 spot for medicine salaries this year. Set in the city of Iowa City, University Of Iowa is a public institution. Students who complete the medicine program here go on to a median salary of roughly $178,334.
Mayo Medical School placed #10 among the highest-paying schools for medicine. Located in the city of Rochester, Mayo Medical School is a private not-for-profit institution. After graduating, medicine degree recipients from Mayo Medical School typically earn about $175,294 annually.
University Of Missouri Columbia earned the #11 position for medicine graduate earnings this year. Set in the city of Columbia, University Of Missouri Columbia is a public institution. Early-career medicine graduates from University Of Missouri Columbia make a median of around $158,239 per year.
Washington University In St Louis came in at #12 for medicine graduate earnings this year. Set in the suburb of St. Louis, Washington University In St Louis is a private not-for-profit institution. Early-career medicine graduates from Washington University In St Louis make a median of around $152,246 per year.
University Of Missouri Kansas City landed the #13 spot for medicine salaries this year. Located in the city of Kansas City, University Of Missouri Kansas City is a public institution. Students who complete the medicine program here go on to a median salary of roughly $130,195.
University Of North Dakota landed the #14 spot for medicine salaries this year. Set in the city of Grand Forks, University Of North Dakota is a public institution. After graduating, medicine degree recipients from University Of North Dakota typically earn about $66,463 annually.
Saint Louis University Main Campus placed #15 among the highest-paying schools for medicine. Saint Louis University Main Campus is a private not-for-profit school located in the city of Saint Louis. Students who complete the medicine program here go on to a median salary of roughly $65,402.
Narrow Medicine Schools by State
View All Medicine Rankings >
Notes and References
The ranking above is published by College Factual, 2026 edition. Schools are ranked on the median early-career earnings of their medicine graduates, drawn primarily from the U.S. Department of Education (College Scorecard field-of-study earnings and IPEDS).
Ranking method: College Major Earnings · 15 schools evaluated.
*Salary figures reflect median early-career earnings (about 5 years after graduation) and may vary by how long a person takes to complete their degree.
- The Integrated Postsecondary Education Data System (IPEDS) from the National Center for Education Statistics (NCES), a branch of the U.S. Department of Education (DOE), serves as the core of our data about colleges.
- Graduate earnings data comes from the U.S. Department of Education’s (College Scorecard) field-of-study earnings.
More about our data sources and methodologies.